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Tranylcypromine User Reviews & Ratings (Page 5)

Brand names: Parnate

Tranylcypromine has an average rating of 8.4 out of 10 from a total of 118 reviews on Drugs.com. 83% of reviewers reported a positive experience, while 10% reported a negative experience.

Reviews for Tranylcypromine

  • danjsul
  • Taken for 1 to 6 months
  • March 22, 2017

For Depression "This worked really well for me for depression but I also have ADHD and had to stop Adderall​. I actually got low blood pressure from this with headaches and what made it normal was eating cheese and taking Adderall. Would still be taking it if I could get prescribed Adderall at the same time."

9 / 10
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5 Report
  • wits...
  • Taken for 1 to 6 months
  • May 3, 2020

For Depression "4 weeks now on Parnate and I'm feeling like my old self again! I can laugh again, take things in my stride, wake up with enthusiasm to face the day. My GP said, "most people are feeling more depressed right now with the social isolation, uncertainty of the pandemic so this must be working". It took me months of. research and trepidation to try it, after a year of worsening depression due to carer stress. Had tried Zoloft, Pristiq and Lexapro in the past. Food restrictions are manageable, no side effects apart from broken sleep. Recommended"

9 / 10
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3 Report
  • Eulipia
  • February 15, 2017

For Depression "My experience of tranylcypromine [Parnate] was very positive from the beginning. The first time I was administered 20mg I felt suddenly much better than I had for weeks. I wanted to go outside and 'see the world'. So far so good. Now comes the Kick In The Head. In the UK 30mg is the highest that they can prescribe. However I tried up to 60mg and it has been beneficial and I have come across blogs and psychiatric accounts on the web that suggest that this dose is ok in the USA That would never happen here in the UK. The guidelines stop at 30mg per day which is unacceptable in the UK especially since the price was increased to £25.00 per 28 tablets. I have had pressure applied from my GP to stop using this drug."

2 / 10
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3 Report

Frequently asked questions

  • Ghost...
  • Taken for 6 months to 1 year
  • July 10, 2019

For Depression "The heart palpitations from Parnate are my only complaint. I eat only fresh Whole Foods with no Tyramine, but the heart palpitations are relentless on this drug. (No blood pressure problems with Parnate, just bad heart palpitations which should not be happening considering that my cardiologist gives my test an A plus. It’s the only antidpressant that actually works for me, but now I must stop because the heart palpitations from Parnate are almost as bad as my depression. All that left now is ECT so I guess soon I can kiss my memory goodbye."

7 / 10
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2 Report
  • Ash
  • Taken for 2 to 5 years
  • October 25, 2016

For Depression "Parnate in my experience has been the most effective AD for anxiety. For me none of the SSRIs/SNRIs worked. I've taken 30-40mgs for ~ 2 years on and off. It's not perfect. It has it's issues. That said it actually helps with anxiety which is A . Caused no weight-gain, no sexual issues. Side effects were: Red eyes, not really being able to tolerate much alcohol, feeling a little 'weird'. Only thing to note is drug interactions. I stuipdly took ecstasy while on this which was a very fast way to a blackout, seizure and ambulance bill. Do not take anything that will affect Serotonin at the same time as this medication. Drug interactions are very serious. That said food reactions imo are exaggerated."

9 / 10
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3 Report

Are you taking this medicine?

  • Anonymous
  • Taken for less than 1 month
  • September 6, 2012

For Depression "I'm 62 and have suffered from depression ever since I can remember,and through the years have only had moderate success with all the other medicines. This one is horrible after only two days I was off the wall, breaking things, screaming and other nasty responses. There is nothing like feeling hopeless again."

1 / 10
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1 Report
  • John...
  • Taken for 1 to 2 years
  • December 8, 2022

For Depression "Of all the anti-depressants I’ve tried, this one was by far the most effective. It was the first time I felt like “this is what normal people feel like getting up in the morning “. The downside is the multiple interactions and food restrictions. I got more and more sensitive to food restrictions, to the point that one piece of salami would send my blood pressure to 160 and require my immediate blood pressure medicine. You need to be very careful what you eat, especially as you take it longer."

9 / 10
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  • Lolly...
  • October 18, 2019

Parnate (tranylcypromine) for Depression "This medication Parnate saved my life!! NO OTHER medication worked. I've been taking it for 5 years and got my life back. Please, please bring it back."

10 / 10
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40 Report
  • chester
  • Taken for 5 to 10 years
  • April 13, 2019

Parnate (tranylcypromine) for Depression "Parnate really works for my depression and makes all other drugs for depression look like a joke."

10 / 10
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39 Report
  • cloudy
  • Taken for 10 years or more
  • May 22, 2018

Parnate (tranylcypromine) for Depression "Parnate is my favorite antidepressant. It took me from suicidal to happy in less than 48 hours."

10 / 10
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36 Report
  • Greg
  • Taken for 5 to 10 years
  • July 3, 2018

Parnate (tranylcypromine) for Depression "Parnate is the only antidepressant worth taking. "

10 / 10
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33 Report
  • Anonymous
  • Taken for 10 years or more
  • June 16, 2016

Parnate (tranylcypromine) for Depression "when nothing else works long term, this is the one. Pain to have to watch what you eat since it's an maoi, but it's better than not having it!"

9 / 10
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40 Report
  • JRano
  • Taken for 1 to 2 years
  • April 13, 2019

Parnate (tranylcypromine) for Depression "This medicine literally saved my life. I've tried them all and only the MAOI class of drugs actually work."

10 / 10
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28 Report
  • Orkideh
  • November 9, 2012

Parnate (tranylcypromine) for Depression "It may include some side effects, I used and I prefer Parnate with some side effects vs depression that's my experience."

10 / 10
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43 Report
  • Johnny...
  • Taken for 5 to 10 years
  • November 15, 2012

Parnate (tranylcypromine) for Depression "5 years on Parnate. Have tried numerous antidepressants and Psycho Drugs, this is only one that has worked. Also take 2 mg/day Suboxone it helps some how."

9 / 10
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42 Report
  • maiiia
  • September 14, 2017

Parnate (tranylcypromine) for Depression "A miracle drug for my depression!!!"

10 / 10
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27 Report
  • Rosey
  • January 6, 2021

Parnate (tranylcypromine) for Depression "Parnate was great for depression but it didn’t really help with anxiety at all. Coming off it has been a nightmare! Going to try Nardil next if I can track supply down"

5 / 10
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12 Report
  • Heather
  • Taken for 6 months to 1 year
  • May 3, 2023

Parnate (tranylcypromine) for Depression "Drinking milk and other foods is not recommended. It made me so nauseous. Sadly I'd forget and then get sick."

4 / 10
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  • Mindf...
  • Taken for 5 to 10 years
  • October 17, 2019

For Depression "Bring back parnate. It's urgent for me!!!"

10 / 10
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  • davow
  • Taken for 6 months to 1 year
  • October 24, 2017

For Depression "worked well for its immediate effects, did nothing noticeable in the long term."

5 / 10
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0 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.