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Topiramate for Weight Loss (Obesity/Overweight) User Reviews

Brand names: Topamax, Trokendi XR, Eprontia, Qudexy XR

Topiramate has an average rating of 7.3 out of 10 from a total of 204 reviews for the off-label treatment of Weight Loss (Obesity/Overweight). 63% of reviewers reported a positive experience, while 17% reported a negative experience.

Topiramate rating summary

7.3/10 average rating

204 ratings from 234 user reviews.

Compare all 38 medications used in the treatment of Weight Loss (Obesity/Overweight).

10
35%
9
15%
8
13%
7
6%
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5%
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6%
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2%
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2%
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5%
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9%

Reviews for Topiramate

  • Sunny
  • Taken for 6 months to 1 year
  • October 25, 2019

Topamax (topiramate) "I was prescribed Topamax for migraine headaches and weight loss. Being on Depakote, my weight had shot up 25 pounds with no end in sight. I was even craving sweets, which I had never done. After two days of Topamax, my appetite decreased noticeably. After a week, I had lost 7 pounds. By the time I had been on it for a month, I was down to 125 and still not hungry. Eating became something I thought I should do instead of something I HAD to do. When my weight dropped to 118, I stopped the Topamax, thinking, if I start to gain weight I’ll take it again. It’s been six years since I’ve taken Topamax and I weigh 130; 20.4 BMI. The results seem to last. I’m not sure it worked for my migraines, but it’s awesome for weight loss!"

10 / 10
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627 Report
  • Happy...
  • Taken for less than 1 month
  • May 24, 2013

Topamax (topiramate) "I have been on Topamax for a little less than a month and already lost 16 pounds! My doctor gave it to me for the weight loss effects and I have had no adverse side effects that I know of so far. It rates a 10 in my book!"

10 / 10
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776 Report
  • Twin
  • Taken for less than 1 month
  • March 8, 2020

"I have been prescribed Topamax 25 at bedtime due to overeating and sleepless nights associated with depression and medication weight gain. I have been on it for two days now, and the cravings are still strong as ever. How long does it usually take for it to kick in?"

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367 Report

Frequently asked questions

  • Migra...
  • Taken for less than 1 month
  • May 18, 2014

"Before Topamax, I used to suffer from chronic migraines. I mean 3-4 migraines a week. Been on Topamax for nearly 3 weeks, day one 25mg instant appetite suppressant loss. 18.7 lbs in 2 weeks! Inches everywhere, food tastes good, just eat very little of it. I'm never ever hungry, but I enjoy cooking! I have energy, not bogged down with lots of medicines anymore, and not one full migraine! I'm excited to lose weight, it's actually very easy to eat healthy. It's all you crave, and I was a sweet addict. No ugly side effects as described, not on this dosage. So, I hope this has helped someone."

10 / 10
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688 Report
  • Margie
  • Taken for less than 1 month
  • August 29, 2020

"Topiramate is a miracle medication! A godsend for losing weight! I have only had to be on a dose of 25mg topiramate a day, and it has hugely reduced my appetite so that I've been eating very small portions, and only wanted to eat healthy food, and I haven't been thinking about food all the time like I used to. I used to binge eat three times a day, incredibly unhealthy and have unhealthy snacks like chocolate brownies, and spent around $90 a day on Ubereats. On topiramate, I'm rapidly losing weight. I was told by my psychiatrist that I'd start on 25mg, after one week move up to 50mg then after another week go up to 100mg, and she told me all about the side effects especially memory loss. I haven't had any side effects! Perhaps because I've only needed to be on 25mg! Plus, in Australia it's extremely inexpensive. This medication has been incredible and life-changing. I wish I'd found it years ago!"

10 / 10
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267 Report

Are you taking this medicine?

  • Lovel...
  • Taken for less than 1 month
  • May 27, 2014

"I have been on Topiramate 25mg for 1 week to be exact and have lost 8 lbs as of this morning. I feel this has been my savior. I have always been healthy (no high blood pressure, no diabetes, no high cholesterol) however, I've always been obese and worked towards trying to rid myself of the weight in efforts to prevent myself from getting those diseases in the future. This has given me the kick start I need. It reduced my cravings for sweets and carbs as well as suppressed my appetite. I do eat 3 meals a day (or at least I try to when I can remember) but for the most part, I have the same amount of energy. I sleep AMAZINGLY, and haven't had any major side effects as others have mentioned. All good here!"

10 / 10
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506 Report
  • Jo Jo...
  • September 13, 2015

Topamax (topiramate) "I have been overweight and suffer from depression for over 20 years. I admit food was my best friend! After a hysterectomy, the doctor put me on hormone replacement medicine. I was so hungry constantly. All I could think about was eating. Then my doctor put me on Topamax, and I LOVE IT! I went from 252 lbs to now 167 lbs, from size 22 to now size 10. I have to make myself eat, never hungry, and when I am eating, I just try to eat slowly. I do drink water now because even my favorite diet soda tastes terrible. I would tell everyone to try it!"

10 / 10
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439 Report

More FAQ

  • Sherrie
  • Taken for 10 years or more
  • June 24, 2019

"I have been on topiramate (Topamax). I take 200mg 2x a day. The only side effects I get are tingling of the fingers, loss of appetite, and weight loss. I do not get headaches, which I love. My stress level stays down, and I sleep really well at night. My 14-year-old daughter loves it; she says, 'Mom, you're nicer,' and my 3-year-old son is much easier to cope with. From my personal experience, I would keep a scale close by because it can cause rapid weight loss, or it may not for everyone; everyone is different. It did for me; I went from 150 to 118 in 3 weeks on it. To all who are taking a high dosage like myself (400mg a day), be careful and keep a close eye on your weight. That high of a dose can also make you not want to eat for 2 or 3 days at a time. There are times my husband has to make me eat something because I am not hungry; I will just drink coffee, juice, and water, and that is it. So please, just be careful."

10 / 10
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262 Report
  • Acano
  • Taken for 1 to 2 years
  • April 4, 2019

"Ok, so I've been taking topiramate 100mg for almost a year now, and I have to say this drug has been a lifesaver! Less than five months on topiramate and I quit drinking, and I've been sober now for almost a year! My eating disorder and bipolar are under control, and I can honestly say I haven't been able to manage either one in my life before. Here's another awesome thing... I've lost over 50lbs! Bad things: numbness and tingling in hands and fingers, brain fog, carbonated drinks taste flat, and when I up the dose, my temper gets very short, but the temper part goes away in about 2 weeks. All in all, I never want to stop this medicine; it's saved my life and helped me better myself as a parent."

9 / 10
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256 Report
  • Mirac...
  • Taken for 1 to 6 months
  • April 18, 2017

Topamax (topiramate) "I weighed 230 pounds and felt like a cow. I started off on 25 mg 1x a day and noticed no change. So I asked doc to change me to 100 mg twice a day. I just take the 200mg at once. That's when I finally noticed a change. I've lost 45 pounds in 6 months! I'm continuing to lose and my goal weight is 160 since I'm tall so only 25 more pounds to go. I noticed at first pop tasted different but now it tastes fine. I used to love beer but now I don't want it, which is fine since it's so fattening lol. I only eat once or twice a day and the carb cravings are gone. I don't exercise much at all. I have no side effects at all. I'm so glad I found this medication; it really has been a miracle. :)"

10 / 10
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309 Report
  • Holly...
  • Taken for 10 years or more
  • October 22, 2016

"I was prescribed Topamax many years ago before they even offered a generic version and before they could legally prescribe it for obesity! So, my doctor prescribed it to me for migraines because I had a slight history of migraines but she said it would cause weight loss. Oh boy, did it! I was over 200 lbs and in a size 18 pants, within 6 months I was in a size 8 pants! By the time a year rolled around, I was 103 lbs and in a 00!!! No exercise! This is a wonder drug. I felt great! I had quit smoking, cut out all sugars and red meat, minimal alcohol. This medicine affects the addiction part of the brain as well as other areas. It's just amazing! I did warn my friends that I would forget sentences halfway through; in 4 weeks no side effects."

10 / 10
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308 Report
  • Eliza...
  • Taken for 1 to 6 months
  • June 3, 2021

Topamax (topiramate) "I've been on topamax for a month today. I couldn't lose weight for anything. I was originally prescribed it for headaches, working great for the headache as well! I went back to my prescriber today, I've lost 8 pounds in a month on such a low dose so it works and it is absolutely awesome!"

10 / 10
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150 Report
  • Anonymous
  • February 24, 2012

Topamax (topiramate) "Topamax is amazing. I originally took it 6 years ago to prevent migraines and lost 80 lbs as a bonus. At that time, my doctor and I speculated that it would someday be approved for weight loss because I was not his only patient to report changes in the taste of carbonated beverages and chocolate while taking the medication. I also noticed that I did not dream about food while taking the medication, but within 3 months of changing medications, food re-entered my dream content. I am now back on the medication to address chronic pain issues and have already found the same results in weight loss, taste changes, and dream content."

9 / 10
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396 Report
  • momma...
  • Taken for less than 1 month
  • March 21, 2015

Topamax (topiramate) "I have struggled for years with what I thought was just a problem with controlling my hunger. I would never eat around anyone, and then once everyone was asleep, I was starved. I finally saw a psychiatrist for my ADD symptoms, and while he was modifying my medication, he diagnosed me with binge eating disorder. To my surprise, he was right. I had no control. I had always bounced on diets. He started me on Topamax 25mg, and I knew instantly it will work. It has a calming effect. I feel so full, and I am going to bed without eating for the first time in years. I am very thankful. Not every medication is for everyone. I am pleased with this one so far."

10 / 10
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310 Report
  • Farou...
  • Taken for 1 to 6 months
  • May 3, 2013

"I have been on Topamax for around two months. I decided to go on them because I weighed around 105 kgs, I was feeling depressed and I couldn't stop binge eating. Through Topamax, I have lost 10 kgs in one month (that would be around 22 pounds). I feel so much better. My urge to binge eat is gone. I feel human again. I don't feel any side effects. I sleep better than before, I drink more water than before (as much as I should drink, before I didn't drink at all and had problems with my kidneys). When I first started topiramate, I got double vision. I read that this was a common side effect and saw my eye doctor about it. She said that it was because my vision improved a great deal. So, thank you Topamax, My health greatly improved."

9 / 10
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354 Report
  • jackie...
  • March 19, 2015

"I am an African American woman with my natural hair. I have not experienced any hair loss. I have been on topiramate for 10 days. I am taking 50 mg, 1 pill only at night, and I have lost 8 pounds so far. My doctor recommended I take 1 pill for 2 weeks before moving to 2 pills a day. I will probably stick with the one pill because I am losing weight. I do exercise 5 days a week also, so this helps. This pill alone is not going to work; you need to get moving just a little. Treadmill 20 minutes is all I do. You can do it!!!! Good luck..."

10 / 10
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303 Report
  • Stevo
  • Taken for less than 1 month
  • December 19, 2020

"I was given this for sleep. I had not even heard of the weight loss aspect of this drug. Tonight I was looking at my pills to plan my vacation. The name didn't look familiar to me so I looked it up. One of the side effects was weight loss. The funny thing is tonight some family members I had not seen for about 4 week came by and they both asked me how much I had lost. I had just put on a shirt that didn't fit me at all 1 month ago and it was baggy. I was really surprised it fit. So I thought I must have dropped weight. Tonight I got on the scale and I was down to 295 from 313 just 4 weeks ago. I had no idea why until I looked up this drug and then it made sense. I'm only on 25 mg tablets 1 per night. Now I'm looking forward to trying on all my old clothes tomorrow."

10 / 10
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139 Report
  • Robyn
  • Taken for 1 to 6 months
  • September 27, 2018

"I started on 50 mg twice daily. I started at 177lb and it had been 2 months and 2 weeks today. Today I weigh 151 pounds and have gone from a size 11/12 to a size 7/8. While I went on this to treat migraines the weight loss has been a great side effect and was effortless. It did change some of my favorite food tastes and most carbonated drinks tastes 100% flat. BUT I DON'T CARE ."

10 / 10
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202 Report
  • Mizzjad
  • Taken for less than 1 month
  • November 8, 2014

"I've been taking 25mg daily for the past 5 days and already lost 3.8kg or 8.3lbs. It's also been acting as a great mood stabilizer which is awesome because I have bipolar and Seroquel alone wasn't doing enough. Very happy with Topamax so far."

10 / 10
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287 Report
  • Chloe
  • Taken for 1 to 6 months
  • January 10, 2020

"I can't seem to remember anything while taking this pill. I take 100 mg twice a day. Yes it is amazing loosing 2 pounds a day but it is creepy as anything not being able to have my memory and loosing my mind not remembering things."

1 / 10
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147 Report
  • MsWil...
  • Taken for less than 1 month
  • August 12, 2019

"After 10 days of taking this medication I have lost 18 pounds, I take this for headaches as well. The side affects are dry mouth and confusion I sure hope they go away, but I will deal with them. I enjoy the relief from my headaches and the weight loss, I have 60 pounds to go "

10 / 10
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157 Report
  • Kate
  • Taken for 1 to 6 months
  • October 15, 2019

Topamax (topiramate) "I’ve taken this medicine Topamax two separate times. The first time it helped me lose weight and I didn’t have many side effects but went off of it once I got in a serious relationship and heard it can make birth control less effective. However, two years after I got off of it I went back on it because of my binge eating disorder and it was horrible. This time I had side effects I was losing feeling in my hands and feet. My face would go numb. It didn’t really help with appetite. And it started to impact my memory. I almost immediately went off of it. And I’m still experiencing memory issues. I’ll be talking and can’t remember words in the middle of a sentence. Or I’ll tell someone something and then a couple of minutes repeat it because I forgot if I said it or not. Keep in mind I’m 21 and shouldn’t be having memory issues like this. I don’t recommend it..."

2 / 10
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152 Report
  • sanub
  • Taken for less than 1 month
  • November 21, 2019

"I have started Topiramate three weeks ago on 25 mg for the first week then to 50mg the second week, 150mg the third week and today I am increasing the dose to 200 for the rest of my time on the med. The first week I started the med, I immediately started feeling full and that had never in my entire life had happened to me. I had always felt like I could eat at the fullest state, and now one small meal and a few glasses of water was just enough. In three weeks I have lost 8 lb, and that is considering I haven't changed anything in my diet, I haven't cut any carbs or sugar simply because I only eat once a day. Over all, there has been some tingling in my feet, which is so normal and at times I feel it but seeing the results makes me super happy so I will continue on using Toprimate."

9 / 10
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149 Report
  • Becky
  • Taken for 1 to 6 months
  • July 7, 2019

"I started at 50 mg a day My weight was 227lb 4 weeks I am down to 209lb Side effects were tingling in hands and feet. Not too bad snd have gotten better Soda tastes very flat ! Helps a lot with appetite Will continue to take and try to lose another 30 pounds"

9 / 10
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158 Report
  • Anonymous
  • Taken for 6 months to 1 year
  • October 8, 2014

"I have been on topiramate for about 10 months now and have lost almost 60 lbs. I have had no real side effects except a very dry mouth if I don't drink enough during the day while I am at work. My family doctor has been monitoring my weight loss since day one. I also changed my cooking and eating habits and stopped drinking soft drinks and no longer crave sweets unless it is that time of the month. I have been overweight most of my life and I have tried for years to lose the weight by exercising and Weight Watchers but it wouldn't come off and stay off, and now it is!"

10 / 10
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261 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.