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Promethazine for Nausea/Vomiting User Reviews

Brand names: Promethegan, Antinaus 50, Anergan 50, Adgan Phenadoz

Promethazine has an average rating of 8.2 out of 10 from a total of 162 reviews for the treatment of Nausea/Vomiting. 80% of reviewers reported a positive experience, while 12% reported a negative experience.

Promethazine rating summary

8.2/10 average rating

162 ratings from 171 user reviews.

Compare all 175 medications used in the treatment of Nausea/Vomiting.

10
51%
9
21%
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9%
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1%
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4%
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1%
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1%
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2%
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Reviews for Promethazine

  • Anxio...
  • Taken for 1 to 6 months
  • October 27, 2020

Phenergan (promethazine) "I have panic disorder, so when stressed out I get very nauseous and frequently throw up. The pandemic made my episodes more frequent so I went to my doctor. Zofran had no effect on me so they prescribed this pill. It totally cures the nausea. I do get a bit drowsy but since I take it when I’m hyped on adrenaline anyway it’s usually a relief. I only need 1/4 of a pill, which I take an hour or so before eating or if I feel like a panic attack is coming on. I gave it 9 just because it doesn’t help if I take it right when I feel like I’m going to throw up, you need to take it preemptively. But despite this I would recommend this to anyone who gets nauseous due to anxiety! I love that it has no side effects and it has helped so much in my recovery."

9 / 10
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97 Report
  • June
  • Taken for 1 to 6 months
  • September 8, 2020

Phenergan (promethazine) "I have Cyclic Vomiting Syndrome. Believe me, I tried EVERYTHING for my nausea. Zofran, Omeprazole, Dramamine, etc. You name it, I've tried it. Nothing could stop my violent vomiting episodes. Phenergan suppositories are the only thing that could ever put a stop to my nausea and vomiting. The only problem is, it makes me very very tired, so I can hardly function in classes if I have to take it during the day. But I'll take being a little "out of it" over being so sick any day!"

9 / 10
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55 Report
  • Jose
  • Taken for 1 to 6 months
  • June 25, 2016

Phenergan (promethazine) "I was suffering with nausea caused by panic disorder, anxiety, and depression, my physician prescribed me zofran at first, but I did not like the side effect of major constipation. Thus I told my doctor "is there any other MEDs for nausea", he prescribed me phenergan and it's a miracle drug. My nausea is now barely present."

10 / 10
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79 Report

Frequently asked questions

  • Robin...
  • September 14, 2013

Phenergan (promethazine) "I'm going through chemo (Taxol and Carboplatin) for ovarian cancer and Phenergan is great. I sometimes also take Zofran with it because they affect two totally different receptors causing the nausea and both together usually stops the ever present nausea."

10 / 10
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84 Report
  • Momma...
  • June 20, 2014

Phenergan (promethazine) "I have used this medication many times for nausea. It always helps quickly and completely. The only reason it does not get a perfect score is that it knocks me out! I'll be groggy for the rest of the day even with only one dose."

8 / 10
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75 Report

Are you taking this medicine?

  • Anonymous
  • November 4, 2015

Phenergan (promethazine) "I was diagnosed with H Pylori and I was throwing up and nauseated every day for an entire month finally I was hospitalized and they gave me phenergran and God Bless the person who created this drug. Even now when I feel the slightest bit of nausea I take it and it'll knock me out and wake up feeling great"

10 / 10
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63 Report
  • Laura...
  • May 13, 2013

Phenergan (promethazine) "I have chronic pancreatitis and often have persistent nausea and vomiting. I have tried Zofran and a couple of other medications for this but none are as effective as Phenergan. Whether orally or I.V., it takes away the nausea. I have a GJ tube for enteral nutrition. Vomiting can cause the tube to twist and slide out of place so it's imperative to keep it under control. Phenergan does that for me. It also helps with the side effects from the painkillers I must take every day (oxycodone and Dilaudid). I don't know where I would be without it. Phenergan may be old school but it works for me better than any newer medicine."

9 / 10
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74 Report
  • Bethv...
  • July 30, 2016

"I love this drug. I suffer with severe fear of vomiting and after getting prescribed it for insomnia I was over the moon. Not only does it help me sleep. It calms me down and stops all my anxiety nausea :) been taking it a few times a week for about a year and it's helped me out massively. Only bad point Is grogginess the next day but it's so worth it"

10 / 10
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49 Report
  • MamaB...
  • Taken for 1 to 6 months
  • January 14, 2020

"This med is a lifesaver. I take 25mgs when I get super nauseous and it takes it away in 10 to 15 mins. Idk about the making you sleepy part because it doesn't do that to me. However, it gets a 10 on the nausea factor alone."

10 / 10
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29 Report
  • Uncon...
  • Taken for less than 1 month
  • February 23, 2018

"Every time I get sick, whichever virus I contact seems to attack my stomach. No diarrhea or anything, Just constant puking. I would go to the clinic knowing what I wanted, which was promethazine, and after 3 hours and about $130, I get my promethazine prescription. My question is: Why is it a prescription drug in the 1st place? It's not abusive. Sure, it can make you sleepy, but so can Nyquil. My answer is the fact that it keeps clinics and a good amount of doctors in business. If people can cure themselves, what do we need to go to the doctor for? In more ways than good, our healthcare system has twice as many drawbacks than benefits for the people. Just think about it."

9 / 10
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38 Report
  • atypi...
  • Taken for 5 to 10 years
  • May 4, 2020

"For decades, I've dealt with nausea (with & without vomiting). At times it resembles motion sickness, occurring as a passenger in certain vehicles, but most commonly I simply experience an onset of nausea. It dates back to early childhood (now age 39). Two meds effectively treat it for me: ondansetron (Zofran) & promethazine (Phenergan). I opt for promethazine due to price & versatility. If I sense the onset of nausea, I take just 6.25mg (thanks to bi-scored tablets) & proactively treat it. Likewise, if I'm nauseated to the point of being unable to function, I can take 12.5, 18.75 or 25mg- depending on circumstance. I have no significant side effects. It can cause drowsiness (in me) but only sedates if I lie down to sleep. I've taken 25mg many times & gone about my day. I also find it helpful for certain allergies. Its versatile & I love that I can tailor the dose precisely & depend on it. I've been prescribed for a decade, though only find it necessary 5-7 times a month, on average."

9 / 10
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27 Report
  • mommy...
  • Taken for 1 to 6 months
  • August 28, 2015

"This medicine saved my life I had severe nausea couldn't keep anything down. I was at the point where I thought this pregnancy would kill me but my doc introduced me to this medicine and it changed my life. I love it and I always keep it around"

10 / 10
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48 Report
  • Slaz
  • September 24, 2015

Phenergan (promethazine) "I tried this medicine a day after I vomited three times and had that nausea feeling and that next day I vomited once in the morning but when I went to the medical centre they gave me the prescription for phenergan. I fell asleep instantly for two hours and a half and woke up refreshed and my stomach did not hurt for the rest of the day and I didn't vomit ever since. It's the best medicine for nausea and vomiting."

10 / 10
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48 Report
  • Jo...
  • Taken for 1 to 2 years
  • May 25, 2018

"I love promethzine. It helps with my PMSing for nausea. I also have horrible emetophobia, definitely comes in handy. I also use it if I have sickness from the flu and motion sickness for planes. I high recommend this drug!"

10 / 10
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34 Report
  • Yanks
  • Taken for less than 1 month
  • March 9, 2017

Phenergan (promethazine) "Has anyone experienced sadness after starting to take this drug. I am on 25mg for a few days and feel that it has helped with the nausea a little bit with the anxiety but it has made me sleep all day and feel sad. I normally have trouble getting onto strong meds such as anti depressants but I don't know if this is a case of this or something else. I am scared of becoming depressed."

8 / 10
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37 Report
  • Mom2b
  • Taken for 1 to 6 months
  • September 29, 2020

"I have had severe hyperemesis throughout my entire pregnancy. I lose over 40 pounds and couldn’t even keep any water down. I tried so many different medications and combinations of medications and nothing seemed to work. Since being on Promethazine suppositories (as well as liquid zofran and reglan) I have been able to gain enough weight for my baby to grow and I am able to get some sleep with it as well."

10 / 10
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22 Report
  • Katy
  • Taken for less than 1 month
  • May 25, 2020

"This drug is HORRIBLE! I've never done crack, but I imagine this is what they experience-after a short period of sleep, I awoke and was crawling out of my skin! I couldn't stay still( even though I was tired and wanted to), I was compelled to walk circles in my room, then jump on the bed and continuously kick my legs in the air and in circles! This drug is TERRIBLE, especially when Zofran is available!"

1 / 10
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22 Report
  • Woozy
  • Taken for less than 1 month
  • December 21, 2019

Phenergan (promethazine) "Had an outpatient procedure and put into a “twilight sedation”, with additional pain meds through the IV although I can’t recall what that was. The pain meds caused me terrible nausea, and dizziness. I was given a dose of Zofran and a motion sickness patch before surgery to try and prevent this as I get nauseous from pain meds so easily...that didn’t work. I was given 12.5 mg of phenergran and 15 minutes later symptoms had improved greatly. I was able to get dressed and start on my way home, although the nausea was still present somewhat due to the motion of the car ride home. Hit the bed and slept like a rock for four hours, felt sleepy the rest of the evening. Blood pressure did go up some as well, 132/88. Took my usual Beta blocker at bedtime that helped my bp come down."

9 / 10
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22 Report
  • CDiff
  • Taken for 1 to 6 months
  • December 24, 2014

"Got this prescribed to me when I had a bug a few months back. Recently I have had recurring Clostridium Difficile (infection in the stomach) for a few months. I take Promethazine when I feel nauseated and it always works in about half an hour. It makes me extremely tired, but its worth it if it combats the nausea. That being said, it doesn't work for any stomach ailment other than nausea (pain, cramping, bloating). I love knowing it's around just in case I need it. (PS if you are really going to throw up, it will come out the other end after promethazine.)"

10 / 10
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39 Report
  • AmeKaye
  • June 3, 2016

Phenergan (promethazine) "I was prescribed phenergan after having my wisdom teeth removed. When I got home, I immediately fell asleep (still under the influence of the anesthesia). Upon waking and attempting to stand, I began to heave and vomit profusely, but after laying back down and taking phenergan, my symptoms were gone nearly instantly. Would definitely recommend; phenergan was an important part of my recovery!"

10 / 10
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34 Report
  • sunsh...
  • December 14, 2014

"I am pregnant and have severe nausea so my doc gave me these pills. They are amazing but they act like a sleeping pill. I went to bed at 5 pm and woke up at 7 am next morning. I like not feeling sick but I don't like sleeping so much when I take it."

9 / 10
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37 Report
  • Tiffa...
  • January 18, 2013

"I suffer from severe anxiety, irritable bowel syndrome, and acid reflux disease. I have inflamed intestines quite often, which causes me to feel nauseous and on the verge of vomiting a few times a week. I got this medicine through an I.V. when I went into the Hospital for severe stomach pains, and was highly nauseous. It worked so well and relaxed me, I fell asleep for a few hours. They gave me a bottle and told me to use as needed. Now, when I have that feeling coming on, I'll pop one of those and relax & sleep it off. Always wake up feeling much better!"

10 / 10
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42 Report
  • suzan...
  • June 10, 2021

Phenergan (promethazine) "I was given phenergan in the hospital when zofran wasn’t doing enough for my nausea due to food poisoning. They put a large amount into my IV and a few minutes later I realized I couldn’t tell if I was dreaming or awake. I keep staring at my husband wondering if he was really there or not (he was) . It was the most frightening medical experience I have ever had. I just kept my mouth shut and didn’t tell anyone what what happening to me because I didn’t want to be given any more medicine. It did get rid of my nausea though, but not even close to being worth it...so terribly frightening."

1 / 10
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15 Report
  • Sweet...
  • November 19, 2014

"I only take promethazine when I'm severely nauseous to the point where I can't unclench my teeth. And let me tell you right now that this pill is magical. After half an hour the nausea is completely gone. But I've never gotten sleepy with it. I've actually had no side effects."

10 / 10
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35 Report
  • EmmyG
  • October 5, 2016

"I have HG, and I've thrown up almost every hour in the hour. I was hospitalized twice before they finally gave my Promethazine. I wasn't able to keep down the oral medication but I opted finally for the suppositories, and while it takes about 30 minutes for me to feel completely better, it's truly a life saver."

10 / 10
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29 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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