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Ondansetron for Nausea/Vomiting User Reviews (Page 4)

Ondansetron has an average rating of 7.7 out of 10 from a total of 382 reviews for the treatment of Nausea/Vomiting. 72% of reviewers reported a positive experience, while 20% reported a negative experience.

Reviews for Ondansetron

  • Mule
  • Taken for 1 to 6 months
  • May 22, 2020

Zofran (ondansetron) "Zofran is a total waste of medication. Literally does NOTHING for me. Off brand pepto does better. My wife has been given it several times in the hospital for the same thing. No results. Seems like the hospitals try to force this particular nausea medicine first. I’m guessing because it’s cheaper."

1 / 10
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  • Kelly
  • May 24, 2019

"The first time I took Zofran was when I had Hyperemesis Gravidarum (unholy morning sickness that lasts the entire pregnancy) when I was pregnant with my twins. My HG was so bad I kept landing in the hospital for dehydration. At first the 8mg pills worked like a miracle but my HG got out of control so I was put on a Zofran pump. Then I got pregnant again 3.5 years later and HG reared its ugly head again. Scoot ahead a few years and my twins had their tonsils and adenoids out and were given Zofran 4mg to help with immediate recovery out of surgery. Then my entire family was struck down from the worst GI bug I've ever encountered (and there have been a few with 3 kids in school) and my doctor prescribed disintegrating 4mg Zofran for everyone and it was such a relief. My husband and I were so sick we could barely lift our heads up to care for the kids but the Zofran allowed us to keep moving. I will forever be grateful for Zofran in all its forms and dosages."

10 / 10
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  • Lee
  • Taken for less than 1 month
  • May 24, 2019

Zofran (ondansetron) "Wow! I went to the ER on Tuesday night and it is now Friday and I was given Zofran for my nausea on top of everything else I was dealing with and this crap has made me nothing but nauseous with lots of throwing up and constipated! Not sure how long this is suppose to last, but it’s freaking annoying and I definitely don’t see myself taking this ever again."

1 / 10
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Frequently asked questions

  • John
  • Taken for 1 to 6 months
  • October 7, 2019

Zofran (ondansetron) "So, I suffer from Cannabinoid hyperemesis syndrome (CHS) because of smoking pot for the last 5 years and I have to say, what has helped is Zofran - it is really good at doing what it’s designed to do ( helps nausea and vomiting) and eased the tension on my stomach, been using for a month every day 2 hours before smoking whatever ie concentrates or just bud. The Ondansetron is miraculous and will literally save you a ton of time since when I was constantly vomiting I couldn’t do my daily routine (going to work, hanging with friends) man I couldn’t even move at all, I was constantly in my bed throwing up..."

8 / 10
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  • Fizzle
  • December 13, 2014

Zofran (ondansetron) "I have been having a lot of stomach issues. I was told it was a bunch of things. At last it took about 4 months to conclude it was my colon. After a bout in the hospital I was given Zofran which worked wonders in no time at all; was also given Phenergan at one point and immediately became extremely irate until I passed out from it. In comparison Zofran is a God send. Can be expensive."

10 / 10
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Are you taking this medicine?

  • Deelish
  • October 28, 2016

"This is a wonder drug! As an emetophobe norovirus season reasonably stresses me out. This med has worked wonders for me! Just a few days ago my 3 yr old woke up projectile vomiting everywhere with a high fever. This mama panicked. He was so ill the pedi Dr told me to take him to the ER. He was vomiting every 10 mins at this point. They gave him a Zofran tablet and he was better within 30 mins, with a script for liquid Zofran to come home with. Of course I feel ill as I have been exposed to the virus repeatedly. I took Zofran liquid this morning and the nausea is gone! I am at work and no need to vomit. I am terrified of throwing up and will deal with the side effects of needed."

10 / 10
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  • fiona...
  • Taken for 1 to 6 months
  • January 16, 2014

"Pregnant in 1994, I was the first person in Scotland to take this medicine, injected, and it saved my life and that of my unborn child, scared and feeling at a loss it worked wonders. I was so thin, dangerously thin, dangerously ill, what a turn around in the space of one week. First thing I ate in 7 months came thanks to Zofran. I would recommend this to anyone who is suffering severe hyperemesis during pregnancy and not to worry, it worked out fine for me and my child who is now 19 and has an amazing life thanks to ondansetron (Zofran)."

10 / 10
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  • Anonymous
  • October 2, 2011

Zofran (ondansetron) "Zofran is a life saver! Works quickly and very well. I get bad anxiety and worry a lot which causes recent and sometimes unbearable stomach upset. One pill and I'm good! I am so happy I found relief. It does cause constipation for me but I'd much rather deal with that!"

8 / 10
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  • Anonymous
  • May 26, 2008

Zofran (ondansetron) "This really is a life saver. I'm 17 weeks pregnant and have cripling morning sickness. So bad that I could not eat or drink anything for over a week. As soon as I took one pill I became 100000000 times better. I would recommend this pill to anyone. I love it. 10 out of 10 in my book."

10 / 10
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  • Jackie
  • Taken for 1 to 6 months
  • June 18, 2019

"I get AWFUL hormone-related nausea every month at the beginning of my periods. It often (not always) happens at the same time as my menstrual cramps and it keeps me up at night and prevents me from working during the day. Ondansetron/Zofran does what it’s supposed to, knocks out the nausea in about 30 min, with the only noticeable side effect being very slight drowsiness? The tiny pills are easy to swallow with a very small amount of water, good when almost everything is making you heave. Couldn’t ask for a better medication for this purpose."

10 / 10
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  • Brit
  • February 2, 2016

Zofran (ondansetron) "Was given this drug while pregnant for morning sickness. Didn't help at all, gave me a headache and actually made me throw up a few times. My son was also born with a genetic mutation - Epidermal Nevus syndrome which I'm sure is from the Zofran as it is not approved for use during pregnancy. If I could go back in time I would NOT have used this during pregnancy. I was also given this drug several times for gastroenteritis with the same result - headache and increased vomiting. Did not work for me."

1 / 10
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  • Me r X
  • Taken for less than 1 month
  • November 9, 2015

Zofran (ondansetron) "Zofran is great for nausea, but watch out for the constipation. I was prescribed 15 8mg tablets last week and have used one tablet a day since then (about 5 days now) and after waiting, walking, drinking copious amounts of water, I am going to need to try a suppository, or laxative, and have my dosage of zofran decreased to 4 mg. Great medication, it DOES give me nausea relief, just something to be prepared for, I know I wasn't."

8 / 10
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  • Anonymous
  • April 5, 2010

Zofran ODT (ondansetron) "I must say I don't have cancer, and I don't have a disease, I have a spas mastic colon which in turns gives me a severe case of Irritable Bowel Syndrome with Constipation. I usually have a bowl movement every 6-11 days and when I do, I get extremely ill with uncontrollable vomiting due to the pain. I've tried several NON dissolving medications and I've found that Zofran ODT (8mg) is the best and I will stick with it as long as it continues to work for me. I hope someone finds this helpful. If you have any form of illness that causes severe vomiting I recommend Zofran ODT."

10 / 10
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  • I...
  • March 29, 2021

Zofran (ondansetron) "Zofran is amazing. Absolutely amazing. My entire life I have feared throwing up. Not sure why but I now have anxiety because of it. I found out I was pregnant and was slightly nauseous all day everyday but with someone who fears vomiting greatly, I was scared and upset. My doctor finally prescribed me zofran after visiting the hospital for nausea and it has been helping me ever since. I have been taking it for 4 years now whenever I need it And it takes it away immediately. So thankful"

10 / 10
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  • Mari-...
  • April 30, 2016

Zofran (ondansetron) "I've been dealing with extreme nausea and vomiting for the past 6 months, and it finally got to the point where I couldn't take it anymore and went to the ER. They gave me Zofran through IV and was feeling better in about an hour. After I was released I was on 4 mg every 8 hours and for about a week I was back to my old self. Then things started to go down hill, and they boosted it to 8 mg. Now it doesn't evenwork anymore and makes me more nauseous than I was before. I also got pretty bad constipation and headaches after taking the medication. Not to mention, if you're taking the tablets be ready to handle the taste because it is DISGUSTING."

5 / 10
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  • GCano
  • Taken for 1 to 2 years
  • January 15, 2019

Zofran (ondansetron) "Since a child I’ve always been nausea prone. Sometimes there would be a direct correlation such as motion (car more often) sickness, over eating/ unhealthy eating, etc. Mostly it just comes out of no where and stops me in my tracks. Without insurance it was very expensive (not sure how much, but $$$). Ever since having insurance and paying a few dollars I will never be caught dead without a couple tabs on my person!!! My GI was very understanding and prescribed 60 tabs a month (up to 2 a day) with a generous amount of refills!!! Only once did it not work but that was on New Years and I believe for obvious reasons!! I’ve not really noticed side effects since my nausea throws off my body anyway. I take this med at least once a week. I can’t believe I wasn’t introduced to this sooner!!!!!!! It’s saved my life"

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  • Anonymous
  • Taken for less than 1 month
  • December 13, 2012

Zofran (ondansetron) "My daughter was experiences a constant unexplained ache in her stomach and a feeling that she was going to throw up, that no stomach test could find. 3 months later an MRI showed she had an AVM in her brain. Surgery to repair took all symptoms away. 3 years later she started having the same feelings. Found out the feeling of throwing up was the aura before partial seizures they didn't know she was having. Still was having the gnawing ache. One amazing doctor suggested Zofran...it was our miracle. She has been fine ever since."

10 / 10
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  • Britt...
  • June 18, 2017

Zofran (ondansetron) "I have a variety of GI issues as well as a phobia of throwing up and ever since I've been taking Zofran ODT, I've been able to function without throwing up in the middle of the night every night. My only complaint would be that after 5 years of taking it, it doesn't work as magically as it did at the start, but it still works wonders."

10 / 10
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  • Lorilo
  • Taken for less than 1 month
  • July 16, 2019

Zofran (ondansetron) "I caught a stomach virus last winter and was vomiting repeatedly. I couldn't keep anything down. I was nauseous, dizzy,and feverish. I felt like I was on a moving boat and I couldn't move or even think without vomiting. After I threw up bile the 2nd day, I went to the ER. I vomited in the waiting room and 3 more times in the exam room. I was given Zofran, which helped a lot. I only threw up 2 or 3 more times after that. I was diagnosed with norovirus."

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  • Anonymous
  • Taken for less than 1 month
  • August 20, 2012

Zofran ODT (ondansetron) "Whole family in hospital for stomach virus with severe nausea and vomiting every half hour. This medicine completely stops the nausea within minutes! It definitely gives you headaches and makes you sleepy, but this is a small price to pay to stop the nausea when you are in that situation. "

10 / 10
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  • Zofran...
  • Taken for less than 1 month
  • June 28, 2022

Zofran (ondansetron) "I am having severe digestive issues and we are trying to figure out what it is. Gastritis? Gallbladder attack? (I do have a gallstone) IBS? Ulcer? Just don’t know. I have horrible anxiety and stress when something is wrong with me. That probably adds to the nausea. I get nauseous and it hurts like a gnawing pain. I can’t really eat, it’s miserable. Went to the ER twice and they administered Zofran, let me tell you! It is a miracle drug! Painful nausea gone! I feel so much more calm and the gas/bloating is gone. I didn’t experience any effects. Even if I get sleepy, it’s a welcomed side effect after feeling yucky for days! Give it a try!!"

9 / 10
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  • silve...
  • Taken for 1 to 6 months
  • September 18, 2012

Zofran ODT (ondansetron) "I am pregnant and have been suffering from severe nausea and vomiting. I have been taking Zofran for about 25 weeks. The disolving tablet doesn't have an affect on me. I can't keep it down, even after half an hour I will throw up the medication. The rare times I can hold it down, it has no affect on me."

2 / 10
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  • Maria...
  • Taken for less than 1 month
  • October 30, 2013

"I am 7 weeks pregnant and around 6 weeks the "morning" sickness began. I missed 2 days of work because I was miserable. I finally decided to call my doctor because I did not want to be missing work, especially since no one knows yet. It's works great! I can make it through the day at work without constantly feeling like I need to vomit. I still get stomach aches and a little constipation, not sure if it's related to the medicine, but I'd take that over the nausea and vomiting any day.It's a life saver for the work day!"

9 / 10
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  • Barbi
  • Taken for 5 to 10 years
  • November 5, 2019

"I am a puker. I am nauseous a lot. I've had a lot of testing done to try to figure out what this happens. I've got some results, acid reflux, slow digestion. I also get horrible migraines. Zofran is my miracle medication. Normally it just takes 4mg. Sometimes if I'm already puking I have to take 8mg. Years ago I was given Zofran at the hospital thru IV and it worked great. I was released with a script for the oral pills. As soon as I would swallow them, they would come up. I hated it cuz I knew the medicine would work, but I couldn't keep it in my system long enough to work. I stopped taking it cuz I was just wasting it throwing it up every time. The next I was hospitalized I was given the pills that melt under the tongue! GoD SENT! It has mad such an improvement in my life. I always carry zofran with me. Its great that I don't have to take it everyday...just the times I need it."

10 / 10
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  • nicol...
  • October 22, 2014

"I recently started Zofran 4mg for constant nausea and vomiting due to anxiety and panic disorder, severe emetephobia and gastritis and have had great results. It does cause crippling stomach cramps at times and some constipation but those I can handle. I forever thought of Phenergan as my miracle after taking it for 5 years for a failing gallbladder (its removed now) but Zofran has been so much more effective at stopping the constant nausea and allowing me to eat normally again! I love and keep it with me at all times!"

9 / 10
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19 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.

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