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Diphenhydramine User Reviews & Ratings (Page 4)

Brand names: Benadryl, Banophen, Benadryl Allergy, Diphen, ZzzQuil, Unisom SleepGels, Nytol, Benadryl Children's Allergy, Sominex, Dicopanol, Diphenydramine Quick Melt, Snooze Fast, Buckley's Bedtime, Diphedryl, Diphenadryl, Unisom SleepMelts, Unisom SleepMinis, Diphenhist, Beldin, Diphenylin, Twilite, Sominex Maximum Strength Caplet, Unisom Liquid, ConRx Allergy, Hyrexin, Hydramine Cough Syrup, Bydramine, Diphen AF, Diphen Cough, DPH, Aler-Dryl, Allergia-C, Benahist-10, Benahist-50, Benoject-50, Calm-Aid, Genahist, Aller-G-Time, Sleep Tab II, Nytol QuickCaps, Trux-adryl, Valu-Dryl, Diphenyl, Altaryl, Belix, Vicks QlearQuil Nighttime Allergy Relief, Hydramine, Silphen Cough, Hydramine Compound, Nytol Caplet, Compoz Nighttime Sleep Aid, Sleepinal, Help I Can't Sleep, Allermax Diphendryl Banaril Aler-Tab Siladryl Allergy Sleep-ettes D Diphenmax Ben-Tann Dytan Vanamine PD Pharbedryl Histaprin Z-Sleep Simply Sleep Complete Allergy Relief Dytuss Dormin Miles Nervine Scot-Tussin Allergy Sleepwell 2-nite …show all brand names

Diphenhydramine has an average rating of 5.4 out of 10 from a total of 515 reviews on Drugs.com. 43% of reviewers reported a positive experience, while 41% reported a negative experience.

Reviews for Diphenhydramine

  • Anonymous
  • June 4, 2010

Benadryl Allergy (diphenhydramine) for Allergic Reactions "I have taken Benadryl or its generic equivalent for many years. It is very good for itchy throats and ears and all kinds of symptoms, and particularly good for sneezing. If the Benadryl doesn't work, then I know I'm coming down with something more than just seasonal allergies. I try to keep Benadryl with me all the time. There are so many food products that I am supposed to be allergic to that sometimes I take a Benadryl before I eat, especially peanut butter and bananas, two of my favorite foods."

7 / 10
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38 Report
  • richa...
  • March 23, 2023

Nytol (diphenhydramine) for Insomnia "I have used this product for two weeks now and have found absolutely no difference in my sleep pattern. I am still taking nearly an hour to get to sleep, then waking two or three times during the night."

1 / 10
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6 Report
  • Bignal
  • Taken for less than 1 month
  • November 17, 2018

Sominex (diphenhydramine) for Insomnia "Took a half a tablet about an hour before bed. Slept just short of nine hours and probably could have turned over and got a bit more but forced myself up. Felt a bit drowsy for a short time but a lot better than I usually do after my normal 5-6 hours. I would strongly recommend you start at half a tablet and work your way up if necessary as if half a tab does what it did I'd hate to see what the manufacturer recommended two would do. Would give this a ten but should always leave room for improvement :-))"

9 / 10
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19 Report

Frequently asked questions

  • Anonymous
  • Taken for less than 1 month
  • April 11, 2015

Benadryl Allergy (diphenhydramine) for Allergic Reactions "Experienced an allergic reaction during dinner at a new restaurant. Throat started itching terribly so we left and drove to the nearest pharmacy. Used Benadryl syrup because I thought it would work faster. Fixed my allergic reaction in a minute."

10 / 10
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27 Report
  • Abby
  • Taken for less than 1 month
  • June 29, 2020

Benadryl (diphenhydramine) for Urticaria "I was admitted to the hospital with a bad case of hives . I was put on an IV. They injected Benadryl into my IV to help with the hives . Within seconds I couldn't breathe . The nurses had just injected in and we're leaving to do some other errands . I couldn't breathe and I couldn't speak and I knew I was gonna die . I managed to pull myself up in the bed sitting up and started pounding on the side of the bed rails to get attention . That's one of the nurses turned around and saw that I could not breathe. Within seconds I have doctors and nurses around my bed . I now have to list Benadryl as an allergy. I probably should carry a magic bracelet to just in case . That was a horrifying day."

1 / 10
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14 Report

Are you taking this medicine?

  • Anonymous
  • July 25, 2009

Unisom SleepGels (diphenhydramine) for Insomnia "I love Unisom Sleep Gels. I can't go to sleep and then can't stay asleep. This has fixed that with no grogginess next morning, no matter if you sleep 4 or 5 hours or 8 or 9 hours and feel the same. No hallucinations or anything. Best yet it's over the counter and cheap."

10 / 10
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38 Report
  • JJFlash
  • Taken for 1 to 2 years
  • October 20, 2020

ZzzQuil (diphenhydramine) for Insomnia "I consider ZzzQuil a low level sleep aid and that is all I need & it works great for me. I have NO problem falling asleep. I often wake up & can't go back to sleep for 90 minutes. But if I take a 1/2 dose of ZZZquil, I can fall right back to sleep. It does not leave me hungover. My wife & I both take it VERY OFTEN. Probably too often. I'm slightly worried that I am addicted to the non-addictive zzzquil LOL."

9 / 10
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13 Report

More FAQ

  • Anonymous
  • Taken for 6 months to 1 year
  • October 17, 2020

Sominex (diphenhydramine) for Insomnia "I have tried everything non prescriptive for sleep and Sominex really works. I am 6 ft and normal build and only need 1/4 tablet. I've worked out this is the optimal dose for me so I can still function well in a busy job the following morning. Anything more than 1/4 tablet and I feel too groggy to function properly the next day."

9 / 10
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13 Report
  • Cyp
  • Taken for less than 1 month
  • February 22, 2021

Nytol (diphenhydramine) for Insomnia "Have trouble getting to sleep and then wake and can’t get back to sleep. Tried Nytol, followed the instructions exactly and am wide awake at 3am, having gone to bed at 11 and not been able to sleep. Worse off than when I don’t take anything. Complete waste of money!"

1 / 10
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12 Report
  • Tom
  • Taken for less than 1 month
  • February 24, 2019

Sominex (diphenhydramine) for Insomnia "They do help me sleep but I feel really terrible in the morning. Very groggy and very short tempered. Have had to throw the pack out as I feel so awful in the mornings. I've not noticed this to this degree of morning grogginess with other sleeping tablets. Horrible stuff!"

3 / 10
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17 Report
  • Big...
  • Taken for 6 months to 1 year
  • October 31, 2017

Benadryl (diphenhydramine) for Allergic Rhinitis "I have allergic rhinitis. Was prescribed Zyrtec, Allegra and Flonase and I couldn't get relief. A pharmacist suggested Benadryl and its the only med that works. Took a generic brand and all hell broke loose. Went back to the original and I'm feeling much better."

9 / 10
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20 Report
  • JemGa
  • Taken for less than 1 month
  • January 22, 2019

Sominex (diphenhydramine) for Insomnia "I took half of one for a transatlantic flight - it worked well. I woke up at 5 am to land, took a train from Newark to Manhattan, fell asleep for a further delicious three hours once I reached a bed. That would have been impossible without the Sominex. A whole one seems like madness!"

8 / 10
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17 Report
  • Connert
  • April 26, 2017

Benadryl (diphenhydramine) for Allergic Reactions "I have no rest every time I take benadryl. I feel I have a really bad reaction as I feel restless, my body feels like itchy, nauseous and it makes me feel angry feeling restless it really hurts my stomach am I allergic to it? or it a bad reaction"

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21 Report
  • Mano
  • Taken for less than 1 month
  • September 7, 2020

ZzzQuil (diphenhydramine) for Insomnia "ZzzQuil seem to work well the first time I tried it. Felt a bit stiff when I woke up, not sure I even moved. Slept long and hard (that's what she said.) Seriously though, seems legit. Have not tried is second time yet. I took two. Was surprised."

8 / 10
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13 Report
  • broken...
  • Taken for less than 1 month
  • January 25, 2022

ZzzQuil (diphenhydramine) for Insomnia "I have had trouble getting to sleep after I stopped taking Oxy that I had been taking broken ribs. ZZZQuil actually had the opposite effect than what it promised. Was jumpy and couldn't get to sleep for hours. I gave it three days to work and each was the same. Rubbish!"

1 / 10
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9 Report
  • Nuttree
  • Taken for less than 1 month
  • June 4, 2020

Sominex (diphenhydramine) for Insomnia "I took half a Sominex last night to try to get a deep sleep. I slept better but I am a wreck today. Bad headache, nausea and extreme muscle fatigue and weakness. Wondered whether it was the Sominex and reading some of the reviews it looks like it is. Even had to nap this afternoon and still feel awful. Binned it."

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13 Report
  • Anony...
  • August 6, 2008

Simply Sleep (diphenhydramine) for Insomnia "This stuff works ridiculously well. The first time I took it I woke up the next morning and I was instantly wide awake and full of energy it's like nothing I've ever had before. Absolutely no drowsiness carrying on to the next day."

10 / 10
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36 Report
  • diphe...
  • May 3, 2010

Benadryl (diphenhydramine) for Insomnia "Works excellent if you haven't built a tolerance to it. After a few days of use you may find the medicine is less effective than it was when you first used it. Benadryl knocks me out quite quick when I use it, the only problem I have with it is that I tend to oversleep or wake up groggy the morning after, which is generally relieved with some sort of caffeinated beverage."

7 / 10
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33 Report
  • lasho...
  • Taken for 6 months to 1 year
  • September 5, 2017

ZzzQuil (diphenhydramine) for Insomnia "I have used ZzzQuil off and on for a year or so to help me fall asleep. I have noticed that on the nights that I take it (1/2 dose) the next day I experience head shaking tremors that I have to consciously control, especially when I drive. I will no longer take this medication as I am concerned about the side-effect."

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19 Report
  • Anonymous
  • October 7, 2008

Benadryl Allergy (diphenhydramine) for Allergic Reactions "I am severely allergic to all nuts and I always keep a few pills with me. If I eat something that has been in contact with nuts I take two pills or a gulp of the syrup and my itchy mouth and throat, swollen lips are instantly soothed. The syrup does work faster than the pills but pills are lighter to carry around. I once ate a huge piece of hazelnut chocolate and having benadryl on me really saved me. It won't work on severe reaction i.e. eating peanut butter but it is definitely a life saver for all other allergic reactions. I am never without benadryl and my epipen. Only thing to look out for is intense drowsiness, so make sure to be at home to take a long nap when it takes effect."

10 / 10
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36 Report
  • DE19702
  • October 16, 2009

Benadryl (diphenhydramine) for Insomnia "After having scripts for lots of different benzodiazepines and sleeping pills, I still rely on this a couple times a month. The ONLY problem is after a couple of days it loses it's effectiveness. It is perfect for sleep and not feeling drugged."

9 / 10
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34 Report
  • Sickly...
  • Taken for 1 to 6 months
  • June 7, 2019

For Nausea/Vomiting "Have nausea often, especially if I under eat one day, I'll be nauseous and have trouble eating for days on end. I've been given zofran, phenergan, and bentyl at ER. When those ran out and the nausea didn't, I looked on the web and saw Benadryl recommended. It's worked very well for me every time! You will most likely be pretty sleepy though. Plan on some nap time."

9 / 10
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15 Report
  • Ruthie
  • Taken for less than 1 month
  • November 4, 2019

ZzzQuil (diphenhydramine) for Insomnia "I only took ZzzQuil for two nights. Both nights I slept just a few hours and woke up with a bad headache two mornings in a row that Advil didn't help and it usually always does. I also noticed yesterday when watching a football game that my vision was acting weird, blurring like. I DO NOT recommend this to anyone. I have tried many over the counter meds and nothing really works - does nothing at all for me but this stuff made me miserable."

1 / 10
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14 Report
  • DownT...
  • September 26, 2010

Unisom SleepGels (diphenhydramine) for Insomnia "I really like Unisom SleepGels. I work at night, so sometimes I have difficulty sleeping mornings. They help me get the sleep I need, with no grogginess. And I only take them when I'm too hyped up to go to sleep, but I need to sleep. "

9 / 10
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32 Report
  • Power...
  • February 15, 2016

Benadryl Allergy (diphenhydramine) for Allergic Reactions "I couldn't stop coughing for one week, I lost my voice and severe lung pain due to the coughing. Went to see a pulmonologyst and did xrays, the results, negative. My lungs were clear and no infection whatsoever . He recommended me to go to Walmart and buy claritin pills, but I was desperate last night to have a good sleep without coughing all night, I haven't been able to sleep with this horrible killing coughing , not mentioning dry nose, itchy ears, and itchy throat. Last night I took two regular benadryl pills and slept like a babe for 10 hrs straight, the only problem is that I make my living driving and can't take the pills during the day. Probably I will take clartin during the day, but I honestly prefer benadryl, way more effective"

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22 Report

Reviews may be edited to correct grammar/spelling or to remove inappropriate language and content. Reviews that appear to be created by parties with a vested interest are not published. This information is not intended to endorse any particular medication. While these reviews may be helpful, they are not a substitute for the expertise, knowledge, and judgement of healthcare professionals.